Domenica Altavilla Selected Research

Polydeoxyribonucleotides

4/2022	Beneficial Effects of Polydeoxyribonucleotide (PDRN) in an In Vitro Model of Fuchs Endothelial Corneal Dystrophy.
1/2022	Corrigendum: Adenosine receptor stimulation by polydeoxyribonucleotide improves tissue repair and symptomology in experimental colitis.
10/2021	Polydeoxyribonucleotide: A Promising Biological Platform to Accelerate Impaired Skin Wound Healing.
7/2021	Targeting Adenosine Receptor by Polydeoxyribonucleotide: An Effective Therapeutic Strategy to Induce White-to-Brown Adipose Differentiation and to Curb Obesity.
2/2020	PDRN, a Bioactive Natural Compound, Ameliorates Imiquimod-Induced Psoriasis through NF-κB Pathway Inhibition and Wnt/β-Catenin Signaling Modulation.
1/2016	Adenosine Receptor Stimulation by Polydeoxyribonucleotide Improves Tissue Repair and Symptomology in Experimental Colitis.
1/2015	Role of Inhibitors of Apoptosis Proteins in Testicular Function and Male Fertility: Effects of Polydeoxyribonucleotide Administration in Experimental Varicocele.
1/2012	Polydeoxyribonucleotide administration improves the intra-testicular vascularization in rat experimental varicocele.
11/2011	Polydeoxyribonucleotide reduces cytokine production and the severity of collagen-induced arthritis by stimulation of adenosine A(₂A) receptor.
3/2011	Activation of adenosine A2A receptors by polydeoxyribonucleotide increases vascular endothelial growth factor and protects against testicular damage induced by experimental varicocele in rats.

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Domenica Altavilla Research Topics

Disease

22	Wounds and Injuries (Trauma) 10/2021 - 04/2003
14	Inflammation (Inflammations) 04/2022 - 01/2003
14	Ischemia 10/2021 - 10/2004
13	Reperfusion Injury 01/2016 - 08/2003
12	Shock 04/2012 - 01/2002
9	Necrosis 03/2017 - 01/2003
9	Ischemic Stroke 04/2012 - 03/2006
6	Sepsis (Septicemia) 04/2023 - 02/2012
6	Systemic Scleroderma (Systemic Sclerosis) 12/2022 - 08/2013
6	Osteoporosis 01/2022 - 10/2002
6	Neoplasms (Cancer) 11/2021 - 04/2004
6	Brain Ischemia (Cerebral Ischemia) 04/2012 - 03/2006
5	Pulmonary Fibrosis (Fibrosing Alveolitis) 12/2022 - 08/2013
5	Metabolic Syndrome (Dysmetabolic Syndrome X) 06/2017 - 03/2009
5	Insulin Resistance 01/2017 - 03/2005
5	Burns 01/2015 - 04/2003
5	Pancreatitis 11/2014 - 04/2003
5	Myocardial Ischemia (Ischemic Heart Diseases) 04/2012 - 08/2003
5	Stroke (Strokes) 11/2011 - 05/2006
5	Hypotension (Low Blood Pressure) 07/2008 - 01/2002
4	Multiple Myeloma 11/2023 - 10/2016
4	Atherosclerosis 12/2022 - 07/2002
4	Colitis 01/2022 - 01/2016
4	Hypoxia (Hypoxemia) 10/2021 - 10/2009
4	Traumatic Brain Injuries (Traumatic Brain Injury) 08/2020 - 03/2012
4	Varicocele 05/2020 - 03/2011
4	Arthritis (Polyarthritis) 01/2019 - 01/2003
4	Edema (Dropsy) 01/2018 - 01/2003
4	Bone Resorption 01/2017 - 10/2002
4	Duchenne Muscular Dystrophy (Muscular Dystrophy, Becker) 12/2009 - 03/2006
4	Spermatic Cord Torsion (Testicular Torsion) 04/2009 - 10/2004
3	Pneumoperitoneum 01/2023 - 04/2012
3	Stomatitis 02/2022 - 06/2020
3	Osteoarthritis 01/2022 - 01/2011
3	Ulcer 01/2018 - 10/2009
3	Fibrosis (Cirrhosis) 01/2018 - 08/2013
3	Prostatic Hyperplasia (Benign Prostatic Hyperplasia) 03/2017 - 10/2011
3	Brain Injuries (Brain Injury) 06/2015 - 01/2004

Drug/Important Bio-Agent (IBA)

30	Proteins (Proteins, Gene)FDA Link 01/2018 - 01/2002
21	Messenger RNA (mRNA)IBA 05/2020 - 01/2002
20	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 02/2018 - 04/2003
19	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 11/2015 - 01/2002
18	salicylhydroxamic acid (SHAM)IBA 05/2020 - 01/2002
16	GenisteinIBA 06/2017 - 10/2002
16	NF-kappa B (NF-kB)IBA 11/2010 - 01/2002
14	MelanocortinsIBA 03/2014 - 08/2004
12	PolydeoxyribonucleotidesIBA 04/2022 - 05/2008
10	flavocoxidIBA 04/2023 - 12/2009
9	AntioxidantsIBA 02/2022 - 06/2002
9	Purinergic P1 Receptors (Adenosine Receptor)IBA 01/2022 - 10/2009
9	Phosphotransferases (Kinase)IBA 01/2018 - 02/2005
8	Peptides (Polypeptides)IBA 04/2012 - 08/2004
7	InflammasomesIBA 08/2020 - 05/2014
7	Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA 11/2017 - 04/2003
7	Mitogen-Activated Protein KinasesIBA 11/2014 - 02/2005
6	caryophylleneIBA 11/2023 - 01/2019
6	Reactive Oxygen Species (Oxygen Radicals)IBA 12/2022 - 01/2011
6	Adenosine A2A Receptor (Adenosine A2A Receptors)IBA 04/2022 - 03/2011
6	Nitric Oxide (Nitrogen Monoxide)FDA Link 11/2017 - 07/2002
6	Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA 01/2016 - 07/2002
6	Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA 11/2015 - 11/2005
6	Melanocyte-Stimulating Hormones (MSH)IBA 03/2014 - 01/2010
6	NF-KappaB Inhibitor alphaIBA 07/2008 - 01/2002
5	CytokinesIBA 01/2023 - 01/2002
5	LycopeneIBA 12/2022 - 10/2011
5	CateninsIBA 01/2022 - 01/2018
5	LipopolysaccharidesIBA 01/2019 - 06/2002
5	NitritesIBA 02/2018 - 07/2002
5	IsoflavonesIBA 06/2017 - 10/2002
4	CollagenIBA 10/2021 - 08/2004
4	Malondialdehyde (Propanedial)IBA 05/2020 - 11/2015
4	NitratesIBA 02/2018 - 07/2002
4	Glucose (Dextrose)FDA LinkGeneric 10/2012 - 03/2005
4	Adrenocorticotropic Hormone (ACTH)FDA Link 04/2012 - 08/2004
4	Neuroprotective AgentsIBA 03/2012 - 03/2006
4	Interleukin-6 (Interleukin 6)IBA 03/2012 - 04/2009
4	Hormones (Hormone)IBA 10/2011 - 04/2004
4	CeruletideIBA 05/2011 - 04/2003
4	alpha-MSHIBA 08/2009 - 03/2006
4	Mitogen-Activated Protein Kinase 3IBA 02/2009 - 10/2004
4	OsteoprotegerinIBA 05/2008 - 03/2005
4	JNK Mitogen-Activated Protein KinasesIBA 12/2007 - 10/2004
4	Vitamin E FDA LinkGeneric 10/2005 - 06/2002
3	Propylthiouracil FDA Link 12/2022 - 09/2013
3	GlucocorticoidsIBA 01/2022 - 06/2009
3	Cannabinoid Receptors (Cannabinoid Receptor)IBA 11/2021 - 01/2019
3	dinitrobenzenesulfonic acidIBA 10/2020 - 01/2016
3	2,4-dinitrofluorobenzene sulfonic acidIBA 10/2020 - 01/2016
3	Hyaluronic Acid (Hyaluronan)IBA 10/2020 - 01/2003
3	Interleukin-18 (Interleukin 18)IBA 08/2020 - 11/2010
3	Biomarkers (Surrogate Marker)IBA 08/2020 - 08/2013
3	Testosterone (Sustanon)FDA Link 05/2020 - 10/2011
3	Simvastatin (Zocor)FDA LinkGeneric 01/2016 - 02/2008
3	DystrophinIBA 09/2015 - 03/2006
3	3,7-dimethyl-1-propargylxanthineIBA 01/2015 - 11/2011
3	EnzymesIBA 11/2014 - 04/2003

Therapy/Procedure

4	Injections 09/2013 - 10/2004
3	Therapeutics 01/2022 - 10/2016
3	Ligation 01/2015 - 04/2012
3	Punctures 01/2015 - 04/2012